Refractory angina (CCS II-IV)
Patients who remain symptomatic despite optimal medical therapy and are poor candidates for further revascularization. The clearest evidence base (MUST-EECP, IEPR) and the largest treatment effect.
- Stable angina on max-tolerated anti-anginal regimen
- Not a candidate for PCI / CABG, or repeat revasc not advised
- EF ≥ 30%, no decompensated CHF in last 2 weeks